The Foundation supports nationally-significant efforts to ensure the humane treatment, care and well-being of domestic animals and the protection and conservation of endangered wildlife and wildlife in captivity in the U.S. The program supports innovative, comprehensive, solution-oriented models that lead to systemic change, reduce suffering, and foster a more compassionate society.

Domestic Animals support national efforts to reduce the number of homeless companion animals through the development of model high-quality, low-cost spay/neuter services and corresponding public education initiatives. The Foundation also supports public education and advocacy efforts to eradicate animal fighting practices.

Wildlife supports nationally-significant efforts to advance the protection and conservation of wildlife with an emphasis on policy and advocacy work related to threatened and endangered species. Another specific area of interest is the lifelong care of primates rescued from research laboratories, entertainment and/or the pet trade.

Grants made to select animal shelters and wildlife rescue organizations in specific geographic regions are at the Foundation's initiative.